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|Tested species reactivity||Rat , Human , Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Ssynthetic peptide corresponding to residues C(39) S A Y D A R L R Q K V A V K K L S R P F(59) of human MaPK11.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Western Blot (WB)||1-3 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Suggested positive control: human brain tissue, human brain protein.
One of the major signaling pathways used by eukaryotic cells to translate extracellular signals into cellular responses is the MAP (mitogen-activated protein) kinase cascade. So far, four MAPK subgroups (ERK, ERK5, JNK and p38) have been identified in humans. p38 beta is closely related to p38. They differ, however, in that p38 is equally well activated by MKK (MAP kinase kinase) 3, MKK4, and MKK6, while p38 beta is preferentially activated by MKK6. p38 beta also shows a strong substrate preference to ATF2 (activating transcription factor 2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
MAP kinase 11, MAP kinase p38 beta, MAPK 11, mitogen activated protein kinase 11, mitogen-activated protein kinase 11, mitogen-activated protein kinase p38 beta, protein kinase, mitogen activated kinase, 11, p38beta, mitogen-activated protein kinase p38-2, stress-activated protein kinase 2, stress-activated protein kinase 2b, stress-activated protein kinase-2, stress-activated protein kinase-2b, P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38Beta
P38BETA2, p38beta, SAPK2B, P38B, P38b, p38beta2, PRKM11, p38Beta, Sapk2b, Sapk2, p38-2, Prkm11, SAPK2
Protein metabolism and modification Protein modification Protein phosphorylation Signal transduction Intracellular signaling cascade MAPKKK cascade Immunity and defense Stress response Developmental processes Cell cycle