|Tested species reactivity||Human, Non-human primate|
|Published species reactivity||Human, Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Contains||15mM sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Flow Cytometry (Flow)||See 2 publications below|
CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
Genetic mechanism of human neutrophil antigen 2 deficiency and expression variations.
MA1-19597 was used in flow cytometry to study the genetic mechanism responsible for expression variations and deficiency in human neutrophil antigen 2
|Li Y,Mair DC,Schuller RM,Li L,Wu J||PLoS genetics (11:null)||2015|
The frequencies of human neutrophil alloantigens in the Chinese Han population of Guangzhou.
MA1-19597 was used in flow cytometry to report the frequencies of human neutrophil antigens in the major Han ethnic group living in China.
|Xia W,Bayat B,Sachs U,Chen Y,Shao Y,Xu X,Deng J,Ding H,Fu Y,Ye X,Santoso S||Transfusion (51:1271)||2011|