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|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified human plasma AMG|
|Storage buffer||0.01M potassium phosphate with 0.135M NaCl, 2.5mM KCl, 1mg/ml BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Radioimmune Assays (RIA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-14663 targets Alpha2-Macroglobulin in ELISA, IP, and RIA applications and shows reactivity with Human samples.
The MA5-14663 immunogen is purified human plasma AMG.
MA5-14663 detects Alpha2-Macroglobulin which has a predicted molecular weight of approximately 162 kDa.
Product MA514663 is a smaller package size of MIA1201 (formerly sold as a Seradyn product).
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Alpha-2-M; Alpha-2-macroglobulin; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5
A2M; A2MD; CPAMD5; FWP007; S863-7