|Immunohistochemistry (Paraffin) (IHC (P))||5 - 10 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 17 amino acid peptide from 2nd cytoplasmic domain of human F2RL3 / PAR4.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
Percent identity with other species by BLAST analysis: Human, Gibbon (100%) Gorilla, Monkey, Marmoset (94%) Bat, Elephant, Horse (88%) Mouse, Bovine, Pig (82%).
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: coagulation factor II (thrombin) receptor-like 3; Coagulation factor II receptor-like 3; F2RL3; PAR-4; PAR4; Protease-activated receptor-4; Proteinase-activated receptor 4; Thrombin receptor-like 3
Gene Aliases: F2RL3; PAR4
UniProt ID: (Human) Q96RI0
Entrez Gene ID: (Human) 9002
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