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|Tested species reactivity||Dog , Horse , Guinea pig , Human , Mouse , Rabbit , Rat , Cattle|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide directed towards the N-terminal of human ACSL3|
|Storage buffer||PBS with 2% sucrose|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.2-1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Peptide sequence: LDGLASVLYP GCDTLDKVFT YAKNKFKNKR LLGTREVLNE EDEVQPNGKI
Sequence homology: Cow: 93%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 93%
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
LACS 3, fatty-acid-Coenzyme A ligase, long-chain 3, lignoceroyl-CoA synthase, long-chain acyl-CoA synthetase 3, fatty acid Coenzyme A ligase, long chain 3, long-chain-fatty-acid--CoA ligase 3, brain acyl-CoA synthetase II, Acyl-CoA synthetase long-chain family member 3, ACS3, FACL3, PRO2194
C85929, FACL3, PRO2194, Facl3, 2610510B12Rik, Pro2194, ACS3, Acs3