|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Rat / IgG2b|
|Immunogen||Synthetic peptide corresponding to amino acids 185-198 of human AID.|
|Contains||0.09% sodium azide|
|Storage conditions||4°C or -20°C if preferred|
Membrane permeabilization is required for flow cytometry applications. For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul. A suggested positive control for immunohistochemical applications is Germinal centre b cells.
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activation-induced cytidine deaminase; AID; AID, ARP2, CDA2, HIGM2,cytidine aminohydrolase; Cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; Single-stranded DNA cytosine deaminase
Gene Aliases: AICDA; AID; ARP2; CDA2; HEL-S-284; HIGM2
UniProt ID: (Human) Q9GZX7
Entrez Gene ID: (Human) 57379
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