|Tested species reactivity||Human|
|Published species reactivity||Not Applicable|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human MCL-1 expressed in E. Coli.|
|Contains||0.03% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunofluorescence (IF)||1/200 - 1/1000|
|Immunohistochemistry (IHC)||1/200 - 1/1000|
|Western Blot (WB)||1/500 - 1/2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
MA5-15236 targets MCL-1 in IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15236 immunogen is purified recombinant fragment of human MCL-1 expressed in E. Coli.
MA5-15236 detects MCL-1 which has a predicted molecular weight of approximately 37kDa.
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products promote apoptosis and are death-inducing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
|Not Applicable||Not Cited||
The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma.
MA5-15236 was used in immunohistochemistry and western blot to investigate miRNAs uniquely expressed in human intrahepatic cholangiocarcinoma
|Chen L,Yan HX,Yang W,Hu L,Yu LX,Liu Q,Li L,Huang DD,Ding J,Shen F,Zhou WP,Wu MC,Wang HY||Journal of hepatology (50:358)||2009|