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|Tested species reactivity||Guinea pig|
|Host / Isotype||Rabbit|
|Immunogen||A synthetic peptide from the 4th cytoplasmic domain of guinea pig TRPC6 conjugated to an immunogenic carrier protein|
|Storage buffer||whole serum|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:300-1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Reconstitute with 100 ul of distilled water.
Centrifuge to remove any insoluble material.
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
short transient receptor potential channel 3, transient receptor potential cation channel protein 3, short transient receptor potential channel 6, TRPC6 cation channel, putative alternative splice variant gpTRPC6c, trp6
trp6, TRP7, TRP3