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|Tested species reactivity||Horse , Guinea pig , Mouse , Dog , Human , Rabbit , Rat , Cattle|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide directed towards the C-terminal of human MTF1|
|Storage buffer||PBS with 2% sucrose|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Peptide sequence: QSSLVMGEQN LQWILNGATS SPQNQEQIQQ ASKVEKVFFT TAVPVASSPG
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
MRE-binding transcription factor, MRE-binding transcription factor-1, metal regulatory transcription factor 1, metal-responsive transcription factor 1, transcription factor MTF-1, zinc regulatory factor, metalloregulatory transcription factor, Metal-regulatory transcription factor 1, ZRF, MTF-1
MTF-1, Thyls, ZRF