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|Tested species reactivity||Mouse|
|Host / Isotype||Goat / IgG|
|Immunogen||Peptide with sequence C-ESAHIEREEYKLKEY, from the internal region near the C-terminus of SYNGAP1 (aa1169-1183)|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.03-0.1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody is predicted to react with human, rat, dog, pig and cow based on sequence homology.
The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
neuronal RasGAP, ras GTPase-activating protein SynGAP, ras/Rap GTPase-activating protein SynGAP, synaptic Ras GTPase-activating protein 1, synaptic Ras-GAP 1, SYNGAP1, synaptic Ras GTPase activating protein 1, DKFZp761G1421, KIAA1938, MRD5, RASA1, RASA5, synaptic Ras GTPase activating protein 1 homolog