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|Tested species reactivity||Human|
|Published species reactivity||Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified human placenta ALP|
|Storage buffer||PBS, pH 7.4|
|Contains||0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Radioimmune Assays (RIA)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunoprecipitation (IP)||See 1 publications below|
MIA1802 targets Alkaline Phosphatase in ELISA, IP, and RIA applications and shows reactivity with Human samples.
The MIA1802 immunogen is purified human placenta ALP.
MIA1802 detects Alkaline Phosphatase which has a predicted molecular weight of approximately 59 kDa.
MIA1802 was formerly sold as a Seradyn product.
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Expression and characterization of disulfide bond use of oligomerized A2-Pancortins: extracellular matrix constituents in the developing brain.
MIA1802 was used in immunoprecipitation to investigate the oligomerization of pancortins and its role in brain development and function
|Ando K,Nagano T,Nakamura A,Konno D,Yagi H,Sato M||Neuroscience (133:947)||2005|
alkaline phosphatase; alkaline phosphatase Regan isozyme; alkaline phosphomonoesterase; glycerophosphatase; placental alkaline phosphatase 1; placental type; PLAP-1; Regan isozyme
ALP; ALPP; PALP; PLAP; PLAP-1