|Tested species reactivity||Dog, Human|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||CXD40Ig(Fc) fusion protein containing the EC region of human CD40 and Fc region of human IgG|
|Storage buffer||PBS with 1% BSA|
|Contains||0.09% sodium azide|
|Storage Conditions||4°C or -20°C if preferred, store in dark|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Neat|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
The CD40 antigen is a single chain glycoprotein. It is known to be a member of the tumor necrosis factor/nerve growth factor superfamily and shows a significant homology to the Hodgkin and quote;s disease-associated antigen, CD30. CD40 is present on all B cells except plasma cells. It is also found on some epithelial cells, carcinomas and lymphoid dentritic cells. It appears that the CD40 antigen is involved in the transduction of regulatory signals for cellular functions such as B cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.