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|Tested species reactivity||Bovine, Dog, Chicken, Horse, Human, Marsupial, Mouse|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (1263 QKQKRANHRERNKTRGK 1279) of FHOD3 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||15 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
FHOD3 is a novel member of the formin homology family playing an important role in regulation of the actin cytoskeleton. It contains a DAD (diaphanous auto regulatory) domain, an FH1 (formin homology 1) domain, an FH2 (formin homology 2) domain and a GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. FHOD3 is a cytoplasmic protein where the main part of the protein localizes to actin fibers and the remaining part displays filamentous staining. A 1422 amino acid containing formin-related actin-organizing protein, FHOD3 may cause stress fiber formation together with cell elongation and may associate with nestin/NES-based interfilament (IF). Expression of FHOD3 is seen mainly in heart, kidney, and brain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FH1/FH2 domain-containing protein 3; FHOS2; formactin-2; Formactin2; formin homolog overexpressed in spleen 2; formin-family protein FHOS2; hFHOS2
A930009H06Rik; BOS_22165; FHOD3; FHOS2; Formactin2; KIAA1695; mKIAA1695