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|Tested species reactivity||Cattle , Dog , Chicken , Human , Mouse , Primate , Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (97 NQYVNKKFSNQYKA 110) of Rab-7 protein.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||10 µg/ml|
|Western Blot (WB)||0.5-1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Rab7 is a 207 amino acid transport carrier, belonging to the Rab family of RAS-related GTP-binding proteins with 4 GTP/GDP-binding sites and terminates in sequences such as cys-X-cys, cys-cys or a closely related sequence. Rab7 located in specific intracellular compartments is known to be an important regulator of vesicular transport of proteins from early to late endosomes and lysosome biogenesis. Rab7 accelerates thyroid hormone production controlling aggregation and fusion of late lysosomes. It is ubiquitously expressed in most of the tissues and plays an essential role in maintenance of the perinuclear lysosome compartment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
GTP-binding protein (rab7); member RAS oncogene family; PRO2706; RAB7; RAB7, member RAS oncogene family; Ras-associated protein RAB7; ras-related protein BRL-RAS; ras-related protein p23; ras-related protein Rab-7a
BOS_21228; PRO2706; RAB7; RAB7A