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|Tested species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Mouse myeloma cell line NS0-derived recombinant human BMP-1/PCP Ala121-Gln730|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 5% trehalose|
|Storage Conditions||-20° C, Avoid Freeze/Thaw Cycles|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||5-15 µg/ml|
|Immunofluorescence (IF)||5-15 µg/ml|
|Immunoprecipitation (IP)||25 µg/ml|
|Western Blot (WB)||0.1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
In direct ELISAs, approximately 10% cross-reactivity with recombinant human (rh) TLL-2 is observed, and less than 1% cross-reactivity with rhBMP-2, -3, -3b, -4, -5, -6, -7, -8, -9, -10, and -15 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
This gene encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, this gene encodes a protein that is not closely related to other known growth factors. This gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
mammalian tolloid protein, procollagen C-endopeptidase, procollagen C-proteinase 3, BMP1, bone morphogenetic protein 1, OI13, PCOLC, PCP, PCP2, TLD, procollagen C-proteinase
PCP2, PCOLC, OI13, PCP, TLD
Protein metabolism and modification Proteolysis Signal transduction Cell communication Ligand-mediated signaling Developmental processes Determination of dorsal/ventral axis Mesoderm development Skeletal development