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|Tested species reactivity||Cattle , Dog , Guinea pig , Human , Mouse , Rabbit , Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide directed towards the N-terminal of human HIST1H1E|
|Storage buffer||PBS with 2% sucrose|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.2-1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Peptide sequence: MSETAPAAPA APAPAEKTPV KKKARKSAGA AKRKASGPPV SELITKAVAA
Sequence homology: Cow: 93%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%
Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
dJ221C16.5; H1 histone family, member 4; H1 VAR.2; H1.4; H1F4; histone 1, H1e; Histone 1d; Histone cluster 1; histone H1.2; histone H1.4; histone H1b; histone H1e; histone H1s-4; MGC116819
dJ221C16.5; H1-4; H1.4; H14; H1d; H1E; H1F4; H1s-4; H1var2; Hist1h1c; HIST1H1E