|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Chicken, Cat, Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (256 NRRMKMKKINKDRAK 270) of Homeobox protein A9 protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes like cell identity, cell division and differentiation. The HOXA9 gene encodes a class I homeodomain protein which is involved in hematopoesis and myeloid differentiation. It shows different splice variants like a 1.8-kb homeobox-containing transcript in fetal brain, lung, liver, and kidney, and 2.2- and 3.3-kb transcripts in fetal and adult kidney and in adult skeletal muscle. Fusion between the HOXA9 gene and the nucleoporin gene NUP98, a member of the GLFG nucleoporin family, on 11p15 occurs as a consequence of leukemia-associated chromosomal translocations. So NUP98-HOXA9 is associated with the t(7;11)(p15;p15) translocation in acute myeloid leukemia, myelodysplastic syndrome, and blastic crisis of chronic myeloid leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABD-B; homeo box A9; Homeobox gene A7; homeobox protein Hox-1.1; Homeobox protein Hox-1.7; Homeobox protein Hox-1G; homeobox protein Hox-A7; Homeobox protein Hox-A9; homeobox protein R5; homeodomain protein HOXA9; hox-1.1; HOX1; HOX1.7; HOX1G
Gene Aliases: ABD-B; D6a9; Hox-1.7; HOX1; HOX1.7; HOX1G; Hox1r5; HOXA-9; Hoxa7; HOXA9
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