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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the N-terminal half of human TIMP-2.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 1% BSA|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Neat|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|ELISA (ELISA)||See 1 publications below|
PA1-21145 detects TIMP-2 in Human samples.
PA1-21145 has been successfully used in Immunohistochemistry (Paraffin) procedures. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
PA1-21145 immunogen is a synthetic peptide derived from the N-terminal half of human TIMP-2..
Matrix metalloproteinases (MMPs) are a family of enzymes that are responsible for the degradation of extracellular matrix components such as collagen, laminin and proteoglycans. These enzymes are involved in normal physiological processes such as embryogenesis and tissue remodeling and may play an important role in arthritis, periodontitis, and metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Evaluation of gelatinases, tissue inhibitor of matrix metalloproteinase-2, and myeloperoxidase protein in healthy and inflamed human dental pulp tissue.
PA1-21145 was used in ELISA to examine healthy and inflamed dental pulp tissue for the expression of MMP2, MMP9, TIMP2 and myeloperoxidase
|Accorsi-Mendonça T,Silva EJ,Marcaccini AM,Gerlach RF,Duarte KM,Pardo AP,Line SR,Zaia AA||Journal of endodontics (39:879)||2013|
CSC-21K; Metalloproteinase inhibitor 2; testicular secretory protein Li 57; TIMP-2; Tissue inhibitor of metalloproteinases 2
CSC-21K; DDC8; TIMP2