|Tested species reactivity||Mouse|
|Published species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a|
|Immunogen||IL-3 dependent mast cells derived from WB- +/+ mice|
|Contains||0.02% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|ELISA (ELISA)||Assay Dependent|
|Flow Cytometry (Flow)||0.2 ug/10^6 cells|
|Immunofluorescence (IF)||Assay Dependent|
|Immunohistochemistry (IHC)||Assay Dependent|
|Immunoprecipitation (IP)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Miscellaneous PubMed (MISC)||See 1 publications below|
MA5-17836 targets CD117/c-Kit in ELISA, FACS, IF, IHC, IP, and WB applications and shows reactivity with Mouse samples.
The MA5-17836 immunogen is iL-3 dependent mast cells derived from WB- +/+ mice.
This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Consequences of the combined loss of BOK and BAK or BOK and BAX.
MA5-17836 was used in flow cytometry to determine if Bok and Bax have any functional redundancy controlling apoptosis using knock out mice.
|Ke F,Bouillet P,Kaufmann T,Strasser A,Kerr J,Voss AK||Cell death and disease (4:null)||2013|