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|Tested species reactivity||Horse , Human , Dog|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide directed towards the C-terminal of human C1QB|
|Storage buffer||PBS with 2% sucrose|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (IHC)||5 µg/ml|
|Western Blot (WB)||0.5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Peptide sequence: AYNTFQVTTG GMVLKLEQGE NVFLQATDKN SLLGMEGANS IFSGFLLFPD
Sequence homology: Dog: 92%; Horse: 82%; Human: 100%
C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
complement C1q subcomponent subunit B, complement component 1, q subcomponent, beta polypeptide, complement component C1q, B chain, complement subcomponent C1q chain B, Complement component 1, q subcomponent, B chain