|ELISA (ELISA)||Assay Dependent|
|Western Blot (WB)||Assay Dependent|
|Tested Species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human Factor IX (CaFIX-1) purified from plasma.|
|Storage buffer||PBS with 4-5mg/ml BSA|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
MA5-17638 targets Factor IX/IXa in ELISA and WB applications and shows reactivity with Human samples.
The MA5-17638 immunogen is human Factor IX (CaFIX-1) purified from plasma.
Factor IX circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Christmas factor; Coagulation factor 9; Coagulation Factor IX; F9; factor 9; factor IX F9; plasma thromboplastic component; Plasma thromboplastin component; PTC
Gene Aliases: F9; F9 p22; FIX; HEMB; P19; PTC; THPH8
UniProt ID: (Human) P00740
Entrez Gene ID: (Human) 2158
Molecular Function: annexin calcium-binding protein calmodulin enzyme modulator hydrolase intracellular calcium-sensing protein peptide hormone protease protease inhibitor receptor serine protease signaling molecule
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