|Tested species reactivity||Human, Non-human primate|
|Published species reactivity||Human, Mouse|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Human infant thymocytes and lymphocytes from a patient with Sezary Syndrome.|
|Storage buffer||PBS with proprietary stabilizer|
|Contains||0.1% sodium azide|
|Storage Conditions||4° C, store in dark, DO NOT FREEZE!|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||Neat|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
For FACS analysis, use 10ul of the suggested working dilution to label 1x10^6 cells in 100ul.
The recommended shelf-life for this product is 6 months.
The protein encoded by this gene is the CD3-gamma polypeptide, which together with CD3-epsilon, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. Defects in this gene are associated with T cell immunodeficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Disease-specific and inflammation-independent stromal alterations in spondylarthritis synovitis.
MA1-74349 was used in immunohistochemistry to identify novel disease-specific pathways in spondylarthritis synovitis using geneome-wide microarray analysis
|Yeremenko N,Noordenbos T,Cantaert T,van Tok M,van de Sande M,Cañete JD,Tak PP,Baeten D||Arthritis and rheumatism (65:174)||2013|
B cell antigen receptor signaling enhances IFN-gamma-induced Stat1 target gene expression through calcium mobilization and activation of multiple serine kinase pathways.
MA1-74349 was used in flow cytometry to study the mechanism by which B cell antigen receptor signaling enhances IFN-gamma-induced Stat1 target gene expression
|Xu W,Nair JS,Malhotra A,Zhang JJ||Journal of interferon and cytokine research : the official journal of the International Society for Interferon and Cytokine Research (25:113)||2005|
Retention of unassembled components of integral membrane proteins by calnexin.
MA1-74349 was used in immunoprecipitation to investigate calnexin's interaction with incompletely assembled TCR components
|Rajagopalan S,Xu Y,Brenner MB||Science (New York, N.Y.) (263:387)||1994|