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|Tested species reactivity||Horse , Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide directed towards the N-terminal of human FYCO1|
|Storage buffer||PBS with 2% sucrose|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Western Blot (WB)||1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Peptide sequence: PLAQELEATR DSLDKKNQHL ASFPGWLAMA QQKADTASDT KGRQEPIPSD
Sequence homology: Horse: 86%; Human: 100%
This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
FYVE and coiled-coil domain-containing protein 1, RUN and FYVE domain containing 3, zinc finger FYVE domain-containing protein 7, FYVE and Coiled-coil domain containing 1, DKFZp779K1152, FLJ13335, MGC126517, MGC126519, RUFY3, ZFYVE7
CTRCT18, ZFYVE7, RUFY3, CATC2