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|Tested species reactivity||Human|
|Published species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptides of human DOG-1 protein|
|Storage buffer||tissue culture supernatant diluted in TBS, pH 7.6, with 1% BSA|
|Contains||<0.1% sodium azide|
|Storage Conditions||4° C, do not freeze|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||Ready-to-use|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
|Immunohistochemistry (IHC)||See 2 publications below|
Heat-mediated antigen retrieval is recommended prior to staining, using a 10mM citrate buffer, pH 6.0, for 10 minutes followed by cooling at room temperature for 20 min. Following antigen retrieval, incubate samples with primary antibody for 10 min at room temperature. A suggested positive control is gastrointestinal stromal tumor.
DOG1, a novel marker, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of kit or PDGFR alpha mutation status.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Plexiform fibromyxoma (plexiform angiomyxoid myofibroblastic tumor) of stomach: an unusual presentation as a fistulating abscess.
MA1-39415 was used in immunohistochemistry to report on a case of plexiform fibromyxoma of the stomach
|Lee PW,Yau DT,Lau PP,Chan JK||International journal of surgical pathology (22:286)||2014|
Na+/Ca2+ exchangers regulate the migration and proliferation of human gastric myofibroblasts.
MA1-39415 was used in immunohistochemistry to study the mechanisms by which Na(+)/Ca(2+) exchangers modulate human gastric myofibroblast proliferation and migration
|Kemény LV,Schnúr A,Czepán M,Rakonczay Z,Gál E,Lonovics J,Lázár G,Simonka Z,Venglovecz V,Maléth J,Judák L,Németh IB,Szabó K,Almássy J,Virág L,Geisz A,Tiszlavicz L,Yule DI,Wittmann T,Varró A,Hegyi P||American journal of physiology. Gastrointestinal and liver physiology (305:G552)||2013|
anoctamin 1, calcium activated chloride channel; Anoctamin-1; Ca2+-activated Cl- channel; calcium activated chloride channel; Discovered on gastrointestinal stromal tumors protein 1; DOG1; FLJ10261; oral cancer overexpressed 2; Oral cancer overexpressed protein 2; ORAOV2; TAOS2; TMEM16A; Transmembrane protein 16A; transmembrane protein 16A (eight membrane-spanning domains); Tumor-amplified and overexpressed sequence 2
ANO1; DOG1; ORAOV2; TAOS2; TMEM16A