|Tested species reactivity||Human, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide (68 TEYKIDEDGKKFKIVRTF 85) of eIF3G protein.|
|Storage buffer||PBS with 0.05% BSA|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||5 µg/ml|
|Western Blot (WB)||4.0-5 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
eIF3G is an RNA-associated protein involved in protein synthesis. It is a member of the eIF-3 subunit G family and the largest of the eukaryotic translation initiation factor family with eukaryotic translation initiation factor-3 (eIF3) being a multiprotein complex composed of at least 13 different subunits. eIF3G has a RRM (RNA recognition motif) domain and is known to interact with eIF3K. The function of eIF3G is to bind to the 40S ribosomal subunit and promote the binding of methionyl-tRNAi and mRNA. This subunit of eukaryotic translation initiation factor-3 also binds to the 18S rRNA. It is ubiquitously expressed in most tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.