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|Tested species reactivity||Horse , Guinea pig , Goat , Human , Mouse , Rabbit , Zebra fish , Rat , Cattle , Sheep|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide directed towards the N-terminal of human DEGS1|
|Storage buffer||PBS with 2% sucrose|
|Contains||0.09% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:200|
|Western Blot (WB)||0.2-1 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Peptide sequence: GSRVSREDFE WVYTDQPHAD RRREILAKYP EIKSLMKPDP NLIWIIIMMV
Sequence homology: Cow: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Sheep: 93%; Zebrafish: 93%
The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4 ) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulation biosynthetic processing of the EGF receptor. Two splice variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
degenerative spermatocyte homolog 1, lipid desaturase, degenerative spermatocyte-like protein RDES, sphingolipid delta(4)-desaturase DES1, cell migration-inducing gene 15 protein, degenerative spermatocyte homolog, lipid desaturase, delta(4)-desaturase, sphingolipid 1, dihydroceramide desaturase 1, membrane fatty acid (lipid) desaturase, membrane lipid desaturase, migration-inducing gene 15 protein, sphingolipid delta 4 desaturase, sphingolipid delta(4)-desaturase 1, dihydroceramide desaturase, Delta(4)-desaturase, sphingolipid 1, DEGS, DES1, Des-1, FADS7, MGC5079, MIG15, MLD, DEGS-1
DES1, MIG15, AA536663, Mdes, DEGS, FADS7, MLD, DEGS-1, BOS_15651, Des-1, Degs, Des1