|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic 16 amino acid peptide from N-terminal extracellular domain of human GPRC5A / RAI3.|
|Purification||Antigen affinity chromatography|
|Contains||< 0.1% sodium azide|
|Storage Conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
|Tested Applications||Dilution *|
|Immunocytochemistry (ICC)||Assay Dependent|
|Immunohistochemistry (Paraffin) (IHC (P))||8 - 38 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
Percent identity with other species by BLAST analysis: Human (100%) Gorilla (94%) Gibbon (81%).
Retinoic acid plays a critical role in development, cellular growth, and differentiation. The specific function for this retinoic acid-induced gene has not yet been determined; however, it may play a role in embryonic development and epithelial cell differentiation. This gene is a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. This gene may also be involved in interaction between retinoid acid and G protein signalling pathways. RAI3 has been reported in lung, kidney, colon, pancreas, prostate, and small intestine. ESTs have been isolated from amnion, breast, colon, eye, lung, nasal cavity, placenta, skin, uterus, and vessel libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.