|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:5000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 229 of 53BP1 (Uniprot ID#Q12888)|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-34675 targets 53BP1 in ICC, IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-34675 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 229 of 53BP1 (Uniprot ID#Q12888).
Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 53BP1; p202; p53-binding protein 1; TP53-binding protein 1; tumor protein 53-binding protein; tumor protein 53-binding protein, 1; tumor protein p53-binding protein, 1; tumor suppressor p53-binding protein 1
Gene Aliases: 53BP1; p202; p53BP1; TDRD30; TP53; TP53BP1
UniProt ID: (Human) Q12888
Entrez Gene ID: (Human) 7158
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