|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 125 and 363 of Human A2BP1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 20% glycerol|
|Contains||0.025% ProClin 300|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29074 targets A2BP1 in IHC (P) and WB applications and shows reactivity with Human, mouse and rat samples.
The PA5-29074 immunogen is recombinant protein fragment corresponding to a region within amino acids 125 and 363 of Human A2BP1.
Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2BP1; A2BP1; ataxin 2 binding protein 1; ataxin 2-binding protein 1; Ataxin-2-binding protein 1; FOX-1; Fox-1 homolog A; fox-1-like RNA-binding protein 1; FOX1; hexaribonucleotide binding protein 1; hexaribonucleotide binding protein 1 isoform alpha; hexaribonucleotide binding protein 1 isoform beta; Hexaribonucleotide-binding protein 1; HRNBP1; RNA binding protein fox-1 homolog 1; RNA binding protein, fox-1 homolog (C. elegans) 1
Gene Aliases: 2BP1; A2BP; A2BP1; FOX-1; FOX1; HRNBP1; MNCb-3035; RBFOX1
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