|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 110-157 of human ABHD9|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
This antibody detects endogenous protein at a molecular weight of 41 kDa.
Purity is >95% by SDS-PAGE.
The alpha/ beta hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical alpha/ beta hydrolase fold, which consists of an eightstranded parallel alpha/ beta structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The abhydrolase domain-containing protein 9 (ABHD9), also designated epoxide hydrolase 3 (EPHX3), is a 360 amino acid protein and a member of the alpha/ beta hydrolase superfamily. The gene encoding ABHD9 maps to chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ABHD9; abhydrolase domain containing 9; Abhydrolase domain-containing protein 9; EPHX3; Epoxide hydrolase 3
Gene Aliases: 2310063B19Rik; ABHD9; EH3; EPHX3
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