|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 216 and 481 of Human ACOX1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29124 targets ACOX1 in WB applications and shows reactivity with Human samples.
The PA5-29124 immunogen is recombinant fragment corresponding to a region within amino acids 216 and 481 of Human ACOX1.
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACOX; acyl-CoA oxidase; acyl-CoA oxidase 1, palmitoyl; acyl-CoA oxidase, straight-chain; acyl-Coenzyme A oxidase 1; acyl-Coenzyme A oxidase 1, palmitoyl; AOX; PALMCOX; palmitoyl; Palmitoyl-CoA oxidase; Peroxisomal acyl-coenzyme A oxidase 1; peroxisomal fatty acyl-CoA oxidase; SCOX; straight-chain; Straight-chain acyl-CoA oxidase
Gene Aliases: ACOX; ACOX1; PALMCOX; SCOX
UniProt ID: (Human) Q15067
Entrez Gene ID: (Human) 51
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