|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 416 and 637 of Human ACSL3|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29507 targets ACSL3 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-29507 immunogen is recombinant protein fragment corresponding to a region within amino acids 416 and 637 of Human ACSL3.
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ACS3; FACL3; fatty-acid-Coenzyme A ligase; fatty-acid-Coenzyme A ligase, long-chain 3; LACS 3; lignoceroyl-CoA synthase; long-chain 3; Long-chain acyl-CoA synthetase 3; Long-chain-fatty-acid--CoA ligase 3; PRO2194
Gene Aliases: ACS3; ACSL3; FACL3; LACS3; PRO2194
UniProt ID: (Human) O95573
Entrez Gene ID: (Human) 2181
Molecular Function: ligase
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