|Immunohistochemistry (Paraffin) (IHC (P))||Assay-dependent|
|Western Blot (WB)||0.5-2 µg/ml|
|Tested Species reactivity||Dog, Mouse, Human, Rat, Bovine|
|Host / Isotype||Goat / IgG|
|Immunogen||synthetic peptide YEEDGSRAIHRKT (Human) (C terminal).|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-31099 detects ACTR1B from human samples.
PA1-31099 has been successfully used in Western blot applications.
The PA1-31099 immunogen is: Synthetic peptide: YEEDGSRAIHRKT (Human) (C terminal).
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: actin-related protein 1B; ARP1 actin-related protein 1 homolog B, centractin beta; ARP1B; beta-centractin; centractin beta; CTRN2
Gene Aliases: 2310066K23Rik; AA960180; AI851923; ARP1B; BOS_11253; CTRN2; PC3
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