|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human ADA2L|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
TADA2L (transcriptional adapter 2-like), also known as TADA2A (transcriptional adapter 2-alpha) or ADA2-like protein, is a 443 amino acid nuclear protein that exists as 2 alternatively spliced isoforms. While most abundantly expressed in testis, TADA2L is present in all tissues. TADA2L contains one SANT domain and one SWIRM domain, and interacts with GCN5 and GR (NR3C1). Its ability to bind double-stranded DNA allows TADA2L to play a role in chromatin remodeling. Although it makes up part of the PCAF complex, TADA2L is also a component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. The gene that encodes TADA2L contains 71,408 bases and maps to human chromosome 17q12. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to osteogenesis imperfecta, Pendred syndrome, lissencephaly, citrullinemia and Shwachman-Diamond syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADA2-like protein; KL04P; TADA2A; TADA2L; Transcriptional adapter 2-alpha; Transcriptional adapter 2-like; transcriptional adaptor 2 alpha
Gene Aliases: ADA2; ADA2A; AV319371; D030022J10Rik; hADA2; KL04P; TADA2A; TADA2L
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