|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to the C-terminal domain of human ADAMTS2.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol|
|Contains||0.05% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-25179 detects ADAMTS2 from human samples.
PA1-25179 has been successfully used in Western blot procedures.
The PA1-25179 immunogen is a synthetic peptide corresponding to the C-terminal domain of human ADAMTS2.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants. The short transcript encodes a protein which has no significant procollagen N-peptidase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: A disintegrin and metalloproteinase with thrombospondin motifs 2; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; ADAM-TS 2; ADAM-TS2; ADAMTS-3; hPCPNI; NPI; PC I-NP; PCINP; PCPNI; pNPI; Procollagen I N-proteinase; Procollagen I/II amino propeptide-processing enzyme; Procollagen N-endopeptidase
Gene Aliases: ADAM-TS2; ADAMTS-2; ADAMTS-3; ADAMTS2; NPI; PC I-NP; PCI-NP; PCINP; PCPNI; PNPI
UniProt ID: (Human) O95450
Entrez Gene ID: (Human) 9509
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