|Western Blot (WB)||0.5-1.0 ug/ml|
|Tested Species reactivity||Human, Pig|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (KDVDLSQPRKGRKP) corresponding to the internal amino acids of AIRE|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine and rat based on sequence homology.
This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay . Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy .
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AIRE; AIRE1; APECED; APECED protein; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; Autoimmune regulator; autoimmune regulator (APECED protein); autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator (automimmune polyendocrinopathy candidiasis ectodermal dystrophy); autoimmune regulator AIRE; PGA1
Gene Aliases: AIRE; AIRE1; APECED; APS1; APSI; PGA1
UniProt ID: (Human) O43918
Entrez Gene ID: (Human) 326
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