|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 693 and 903 of Human AKAP1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 40% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-27736 targets AKAP1 in WB applications and shows reactivity with Human samples.
The PA5-27736 immunogen is recombinant fragment corresponding to a region within amino acids 693 and 903 of Human AKAP1.
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
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Protein Aliases: A kinase (PRKA) anchor protein 1; A-kinase anchor protein 1; A-kinase anchor protein 1, mitochondrial; A-kinase anchor protein 149 kDa; AKAP; AKAP 149; AKAP121; AKAP149; AKAP84; D-AKAP-1; D-AKAP1; Dual specificity A-kinase-anchoring protein 1; dual-specificity A-kinase anchoring protein 1; mitochondrial; PPP1R43; PRKA1; protein kinase A anchoring protein 1; Protein kinase A-anchoring protein 1; protein kinase A1; protein phosphatase 1; protein phosphatase 1, regulatory subunit 43; regulatory subunit 43; S-AKAP84; SAKAP84; spermatid A-kinase; Spermatid A-kinase anchor protein 84; testicular secretory protein Li 5; tudor domain containing 17
Gene Aliases: AKAP; AKAP1; AKAP121; AKAP149; AKAP84; D-AKAP1; PPP1R43; PRKA1; SAKAP84; TDRD17
UniProt ID: (Human) Q92667
Entrez Gene ID: (Human) 8165
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