|Flow Cytometry (Flow)||3-5 µg/10^6 cells|
|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to residues 319-331 of human AKT2.|
|Contains||0.02% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Suggested positive control: HeLa, antigen standard for AKT2 (transient overexpression lysate).
Akt, protein kinase B (PKB), is a serine/threonine kinase, which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI 3-kinase). Akt2 is amplified and overexpressed in some human cancers.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AKT3; murine thymoma viral (v-akt) homolog-2; PKB beta; PKB gamma; PKBG; Protein kinase Akt-2; Protein kinase Akt-3; Protein kinase B beta; Protein kinase B gamma; putative v-akt murine thymoma viral oncoprotein 2; rac protein kinase beta; RAC-beta serine/threonine-protein kinase; RAC-gamma serine/threonine protein kinase; RAC-gamma serine/threonine-protein kinase; RAC-PK-beta; RAC-PK-gamma; STK-2; v-akt murine thymoma viral oncogene homolog 2; v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
Gene Aliases: AKT2; AKT3; HIHGHH; MPPH; MPPH2; PKB-GAMMA; PKBB; PKBBETA; PKBG; PRKBB; PRKBG; RAC-BETA; RAC-gamma; RAC-PK-gamma; STK-2
Molecular Function: annexin calcium-binding protein calmodulin intracellular calcium-sensing protein kinase non-receptor serine/threonine protein kinase protein kinase transfer/carrier protein transferase
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