|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 318-347 amino acids from the central region of human ALDH2|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse and rat based on sequence homology.
ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: acetaldehyde dehydrogenase 2; Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDH2; ALDHI; ALDM; EC 22.214.171.124; liver mitochondrial ALDH; nucleus-encoded mitochondrial aldehyde dehydrogenase 2
Gene Aliases: ALDH-E2; ALDH2; ALDHI; ALDM
UniProt ID: (Human) P05091
Entrez Gene ID: (Human) 217
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