|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 366 and 703 of Human AMOT|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31196 targets AMOT in WB applications and shows reactivity with Human samples.
The PA5-31196 immunogen is recombinant fragment corresponding to a region within amino acids 366 and 703 of Human AMOT.
This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Angiomotin; angiomotin p130 isoform; angiomotin p80 isoform
Gene Aliases: AMOT; KIAA1071
UniProt ID: (Human) Q4VCS5
Entrez Gene ID: (Human) 154796
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