|Western Blot (WB)||1:500-1:2000|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||synthetic peptide AVSKGDGMRGLAC, corresponding to amino acids 3 - 14 of Human AP2 alpha.|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.02M potassium phosphate, pH 7.2, with 0.15M NaCl|
|Contains||0.01% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
PA1-31776 detects AP2 alpha from human samples.
PA1-31776 has been successfully used in Western blot applications.
The PA1-31776 immunogen is: Synthetic peptide: AVSKGDGMRGLAC, corresponding to amino acids 3 - 14 of Human AP2 alpha.
The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Activating enhancer-binding protein 2-alpha; Activator protein 2; AP-2; AP-2 transcription factor; AP-2alpha; AP2-alpha; AP2TF; BOFS; FLJ51761; TFAP2; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); Transcription factor AP-2-alpha
Gene Aliases: AP-2; AP-2alpha; AP2TF; BOFS; TFAP2; TFAP2A
UniProt ID: (Human) P05549
Entrez Gene ID: (Human) 7020
Molecular Function: transcription factor
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