|Western Blot (WB)||0.1-0.3 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (EASHPSQDGKRQYK) corresponding to the internal amino acids of APBA1|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with mouse and rat based on sequence homology.
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein . It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adapter protein X11alpha; adaptor protein X11alpha; adaptor protein X11alpha amyloid beta A4 precursor protein-binding, family A, member 1; amyloid beta (A4) precursor protein-binding, family A, member 1 (X11); Amyloid beta A4 precursor protein-binding family A member 1; APBA1; D9S411E; mint; Mint-1; MINT1; Neuron-specific X11 protein; Neuronal Munc18-1-interacting protein 1; phosphotyrosine-binding/-interacting domain (PTB)-bearing protein; X11; X11A; X11ALPHA
Gene Aliases: APBA1; D9S411E; LIN10; MINT1; X11; X11A; X11ALPHA
UniProt ID: (Human) Q02410
Entrez Gene ID: (Human) 320
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