|Immunofluorescence (IF)||10 µg/ml|
|Western Blot (WB)||1 µg/ml|
|Tested Species reactivity||Mouse|
|Host / Isotype||Rat / IgG2a|
|Immunogen||Adenomatous polyposis coli protein fused to GST (aa 788-1038)|
|Contains||0.09% sodium azide|
|Storage conditions||Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C|
This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Adenomatous Polyposis Coli; adenomatous polyposis coli protein; APC; DP2; DP2.5; DP3; FPC; multiple intestinal neoplasia
Gene Aliases: AI047805; AU020952; AW124434; CC1; mAPC; Min
Entrez Gene ID: (Mouse) 11789
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