|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 327 and 575 of Human APPBP2|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-31005 targets APPBP2 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-31005 immunogen is recombinant fragment corresponding to a region within amino acids 327 and 575 of Human APPBP2.
The protein encoded by this gene interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing. The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. This gene has been found to be highly expressed in breast cancer. Multiple polyadenylation sites have been found for this gene.
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Protein Aliases: amyloid beta precursor protein (cytoplasmic tail) binding protein 2; Amyloid beta precursor protein-binding protein 2; Amyloid protein-binding protein 2; APP-BP2; HS.84084; PAT1; Protein interacting with APP tail 1
Gene Aliases: APP-BP2; APPBP2; HS.84084; KIAA0228; PAT1
UniProt ID: (Human) Q92624
Entrez Gene ID: (Human) 10513
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