|Western Blot (WB)||1-3 µg/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Peptide with sequence NGVVTSIQDRYGS, from C-Terminus of the protein sequence according to NP_055385|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA1-31452 has been successfully used in Western blot applications. Detects a band around 55 - 60 kDa in mouse brain samples.
The PA1-31452 immunogen is a peptide with sequence NGVVTSIQDRYGS, from C-Terminus of the protein sequence according to NP_055385.
The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ADP-ribosylation factor GTPase activating protein 1; ADP-ribosylation factor GTPase activating protein 3; ADP-ribosylation factor GTPase-activating protein 3; ARF GAP 3; ARF1GAP; HRIHFB2281; MGC39924; RP11-261N11.1
Gene Aliases: ARFGAP1; ARFGAP3
UniProt ID: (Human) Q9NP61
Entrez Gene ID: (Human) 26286
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