|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant protein fragment corresponding to a region within amino acids 123 and 258 of Human ARH|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30505 targets ARH in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-30505 immunogen is recombinant protein fragment corresponding to a region within amino acids 123 and 258 of Human ARH.
The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ARH; ARH1; ARH2; Autosomal recessive hypercholesterolemia protein; FHCB1; FHCB2; LDL receptor adaptor protein; Low density lipoprotein receptor adapter protein 1
Gene Aliases: ARH; ARH1; ARH2; FHCB1; FHCB2; LDLRAP1
UniProt ID: (Human) Q5SW96
Entrez Gene ID: (Human) 26119
Molecular Function: signaling molecule
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