|Western Blot (WB)||0.5-2 ug/ml|
|Tested Species reactivity||Human|
|Host / Isotype||Goat / IgG|
|Immunogen||Synthetic peptide sequence (YEEDGSRAIHRKT) corresponding to the C-terminus amino acids of ACTR1B|
|Purification||Antigen affinity chromatography|
|Storage buffer||TBS, pH 7.3, with 0.5% BSA|
|Contains||0.02% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Actin-related protein 1B; ACTR1B; ARP1 (actin-related protein 1, yeast) homolog B (centractin beta); ARP1 actin-related protein 1 homolog B, centractin beta; ARP1 actin-related protein 1 homolog B, centractin beta (yeast); ARP1, yeast homolog B; ARP1B; Beta-centractin; centractin beta; CTRN2
Gene Aliases: ACTR1B; ARP1B; CTRN2; PC3
UniProt ID: (Human) P42025
Entrez Gene ID: (Human) 10120
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