|Western Blot (WB)||1:500-1:1000|
|Tested Species reactivity||Human, Mouse, Non-human primate|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide derived from the internal region of human ASAH3L|
|Purification||Antigen affinity chromatography|
|Storage buffer||Dulbecco's PBS, pH 7.4, with 150mM NaCl, 50% glycerol|
|Contains||0.02% sodium azide|
The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [PubMed 16940153]).[supplied by OMIM, Jul 2010].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Acylsphingosine deacylase 3-like; alkaline CDase 2; Alkaline ceramidase 2; AlkCDase 2; ASAH3L; cancer related gene-liver 1 (CRG-L1); Cancer-related gene liver 1 protein; ceramide hydrolase; CRG-L1; haCER2; N-acylsphingosine amidohydrolase 3-like
Gene Aliases: 2410116I05Rik; ACER2; ALKCDase2; ASAH3L; CRG-L1; maCER2; PP11646
Molecular Function: hydrolase
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