|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 15 and 377 of Human ASIC1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 10% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-28241 targets ASIC1 in WB applications and shows reactivity with Human samples.
The PA5-28241 immunogen is recombinant fragment corresponding to a region within amino acids 15 and 377 of Human ASIC1.
This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown. Alternative splicing of this gene generates 2 transcript products.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ASIC; 2; ACCN2 variant 3; acid sensing (proton gated) ion channel 1; acid sensing ion channel 1; acid-sensing (proton-gated) ion channel 1; Acid-sensing ion channel 1; acid-sensing ion channel 1a protein; amiloride-sensitive; Amiloride-sensitive cation channel 2, neuronal; ASIC1; ASIC1A; BNaC2; Brain sodium channel 2; Cation channel; Cation channel, amiloride-sensitive, neuronal, 2; hBNaC2; neuronal
Gene Aliases: ACCN2; ASIC; ASIC1; BNAC2
UniProt ID: (Human) P78348
Entrez Gene ID: (Human) 41
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