|Immunohistochemistry (Paraffin) (IHC (P))||1:250|
|Western Blot (WB)||0.5-2 µg/ml|
|Tested Species reactivity||Bovine, Dog, Human, Mouse, Non-human primate, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to an N-terminal portion within residues 1-100 of the human protein [Swiss-Prot# Q676U5]|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 30% glycerol|
|Contains||0.1% sodium azide|
|Storage conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
Suggested positive control: HeLa whole cell lysate.
Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy (Mizushima et al., 2003 [PubMed 12665549]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: apg16 autophagy 16like s cerevisiae; APG16-like 1; APG16L beta; ATG16 autophagy related 16-like 1; atg16l anti; Atg16L1 gamma; autophagy related 16-like 1; autophagy-related 16-like 1; autophagy-related 16-like 1 gamma; Autophagy-related protein 16-1; WD repeat domain 30; wdr30
Gene Aliases: 1500009K01Rik; APG16L; ATG16A; ATG16L; ATG16L1; BOS_3878; IBD10; UNQ9393/PRO34307; WDR30
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